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Drug-coated balloon-only strategy for percutaneous coronary intervention of left main coronary artery

《医学前沿(英文)》 2023年 第17卷 第1期   页码 75-84 doi: 10.1007/s11684-022-0950-1

摘要: This retrospective single-center registry study included all consecutive patients who underwent percutaneous coronary intervention (PCI) for a de novo left main coronary artery lesion using drug coated-balloon (DCB)-only strategy between August 2011 and December 2018. To best of our knowledge, no previous studies of DCB-only strategy of treating de novo left main coronary artery disease, exist. The primary endpoint was major adverse cardiovascular events (MACEs) including cardiac death, non-fatal myocardial infarction, and target lesion revascularization (TLR). The cohort was divided into two groups depending on weather the lesion preparation was done according to the international consensus group guidelines. Sixty-six patients (mean age 75±8.6, 72% male), 52% of whom had acute coronary syndrome, underwent left main PCI with the DCB-only strategy. No procedural mortality and no acute closures of the treated left main occurred. At 12 months, MACE and TLR occurred in 24% and 6% of the whole cohort, respectively. If the lesion preparation was done according to the guidelines, the MACE and TLR rates were 21.2% and 1.9%. Left main PCI with the DCB only-strategy is safe leading to acceptable MACE and low TLR rates at one year, if the lesion preparation is done according to the guidelines.

关键词: drug-coated balloon     left main     high bleeding risk     predilatation     calcifield lesion     percutaneous coronary intervention    

Contemporary coronary artery bypass grafting

null

《医学前沿(英文)》 2014年 第8卷 第4期   页码 395-398 doi: 10.1007/s11684-014-0374-7

摘要:

Current evidence clearly demonstrates that coronary artery bypass grafting (CABG) remains the “gold standard” treatment for most patients with multivessel and left main stem disease. This article summarizes the relevant evidence basis demonstrating that CABG, in comparison to stenting, reduces mortality and subsequent myocardial infarction and the need for repeat revascularization. The article also describes the evidence basis to support the use of more arterial grafts during CABG and the current role of off-pump CABG.

关键词: coronary artery bypass grafting (CABG)     coronary artery disease     left main     arterial grafts     internal mammary artery     off-pump CABG    

Incremental value of contrast echocardiography in the diagnosis of left ventricular noncompaction

null

《医学前沿(英文)》 2016年 第10卷 第4期   页码 499-506 doi: 10.1007/s11684-016-0473-8

摘要:

Contrast echocardiography with left ventricular opacification (LVO) improves the definition of endocardium in two-dimensional echocardiography (2DE). This study was aimed to determine whether LVO offered added diagnostic value in noncompaction of left ventricular myocardium (NCVM). A total of 85 patients (40±20 years, 54 males) with suspected NCVM were subjected to transthoracic 2DE and LVO, and 40 healthy volunteers were examined with 2DE and assigned as control subjects. The location of NCVM, the thickness ratio of noncompacted to compacted myocardium (NCR), and the cavity size and ejection fraction of LV were quantified. Results revealed that NCVM was mainly located in the LV medium (53.2%), apical (46.2%) segments, and lateral wall (39.8%). The NCR obtained through LVO was greater than that detected through 2DE (4.2±1.3 vs. 3.3±1.2, P<0.001), and higher inter-correlations and less intra- and inter-observer variabilities were determined in the former than in the latter. The NCVM detection rates were also increased from 63.5% via 2DE to 83.5% via LVO and 89.4% via 2DE combined with LVO (2DE+ LVO) (= 0.0004). The LV cavity size was greater and the LV ejection fraction (LVEF) was lower in the NCVM patients than in the control group (P<0.01). In the NCVM group, the LV cavity size was higher and the LVEF was lower in LVO than in 2DE (P<0.01). In conclusion, contrast echocardiography contributes significant sensitivity and reproducibility to routine transthoracic echocardiography in NCVM diagnosis. Therefore, this technique should be clinically performed to diagnose suspected NCVM.

关键词: echocardiography     left ventricular noncompaction cardiomyopathy     echo contrast media    

Challenges and opportunities in improving left ventricular remodelling and clinical outcome following

《医学前沿(英文)》 2021年 第15卷 第3期   页码 416-437 doi: 10.1007/s11684-021-0852-7

摘要: Over the last half century, surgical aortic valve replacement (SAVR) has evolved to offer a durable and efficient valve haemodynamically, with low procedural complications that allows favourable remodelling of left ventricular (LV) structure and function. The latter has become more challenging among elderly patients, particularly following trans-catheter aortic valve implantation (TAVI). Precise understanding of myocardial adaptation to pressure and volume overloading and its responses to valve surgery requires comprehensive assessments from aortic valve energy loss, valvular-vascular impedance to myocardial activation, force-velocity relationship, and myocardial strain. LV hypertrophy and myocardial fibrosis remains as the structural and morphological focus in this endeavour. Early intervention in asymptomatic aortic stenosis or regurgitation along with individualised management of hypertension and atrial fibrillation is likely to improve patient outcome. Physiological pacing via the His-Purkinje system for conduction abnormalities, further reduction in para-valvular aortic regurgitation along with therapy of angiotensin receptor blockade will improve patient outcome by facilitating hypertrophy regression, LV coordinate contraction, and global vascular function. TAVI leaflet thromboses require anticoagulation while impaired access to coronary ostia risks future TAVI-in-TAVI or coronary interventions. Until comparable long-term durability and the resolution of TAVI related complications become available, SAVR remains the first choice for lower risk younger patients.

关键词: surgical aortic valve replacement     trans-catheter aortic valve implantation     left ventricular hypertrophy and fibrosis     myocardial force-velocity relationship     His-Purkinje pacing     renin-angiotensin system inhibitors     coronary access impairment    

Key technological innovations in the construction of the main terminal of Beijing Daxing International

《工程管理前沿(英文)》 2022年 第9卷 第4期   页码 689-694 doi: 10.1007/s42524-022-0223-3

关键词: Beijing Daxing International Airport     main terminal     architectural technology innovation    

Evaluation of potential failure of rock slope at the left abutment of Jinsha River Bridge by model test

Zhiming ZHAO, Xihua WANG

《结构与土木工程前沿(英文)》 2013年 第7卷 第3期   页码 332-340 doi: 10.1007/s11709-013-0206-x

摘要: Jinsha River Bridge is located on Tiger Leaping Gorge town, China. The left bank slope composes of moderately thick layer of slate overlain by schistose basalt, and where rocks are controlled by two sets of joint planes. To evaluate the stability of the rock slope under bridge foundation, model test and calculation model based on the geological parameters and the slope stability was simulated and analyzed using Universal Distinct Element Code (UDEC) and Finite Element Mehod (FEM). According to model test, failure mainly initiated at the toe with shear movement along the joint planes, eventually resulting in the sliding along the slope surface and formation of tension crack at the crest of the model. This result coincide with the UDEC model, which shows that slope surface will produce loosening damage and slipping expected along the joint planes under different loading conditions. Moreover, the result of FEM analysis indicates that the rock mass under the main pier has potential shear failure region. So, the bridge foundation should be strengthened to prevent the slope failure under external forces.

关键词: slope stability     strength properties     model test     numerical analysis    

The main and added effects of heat on mortality in 33 Chinese cities from 2007 to 2013

《环境科学与工程前沿(英文)》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1681-5

摘要:

● The main and added effect from heat co-existed in China.

关键词: Heat     Main effect     Added effect     Mortality     Vulnerable population    

Optimization of the main liming process for inulin crude extract from Jerusalem artichoke tubers

Huandong LI, Hongji ZHU, Jianjun QIAO, Junhu DU, Hua ZHANG

《化学科学与工程前沿(英文)》 2012年 第6卷 第3期   页码 348-355 doi: 10.1007/s11705-012-1295-0

摘要: A three-stage homogenate extraction was used as a new method for inulin extraction from Jerusalem artichoke tubers. Compared with the results from conventional hot water extraction, the three-stage homogenate extraction gave higher yields and caused less degradation of the inulin. The inulin crude extract was then clarified by a carbonate-precipitation method, during which three variables — the quicklime mass, the reaction temperature and the reaction time were optimized for the main liming process to give the best clarification effect. A Plackett-Burman design, the path of steepest ascent method, a Box-Behnken design and response surface methodology (RSM) were employed in the experimental design. The optimal conditions for the main liming process were determined to be 12.0 g/L, 71.4°C and 8 min. The confirmatory tests proved that the best clarification efficiency (92.74%) was achieved at these conditions and this was approximately equal to the value predicted by the model.

关键词: inulin     homogenate extraction     Jerusalem artichoke     main liming process    

Construction management and technology innovation for main projects of Quanzhou Bay Bridge

Jun DU, Fangwen WENG

《工程管理前沿(英文)》 2021年 第8卷 第1期   页码 151-155 doi: 10.1007/s42524-020-0147-8

摘要: Hongtao ZHOU, Hongwei WANG, Wei ZENG. [J]. Front. Eng, 2018, 5(1): 78-87.SangHyun LEE. [J]. Front. Eng, 2017, 4(1): 35-40.Bao-long Yuan,Sheng-gang Ren,Xing Hu,Xuan-yu Yang. [J]. Front. Eng, 2016, 3(1): 24-29.Ting Gong,Jian Yang,Hao Hu,Feng Xu. [J]. Front. Eng, 2015, 2(2): 122-124.Hong-yong Liu,Yi-qi Chen,Yi Yang. [J]. Front. Eng, 2015, 2(1): 71-75.Burcu Akinci. [J]. Front. Eng, 2014, 1(3): 283-289.Mao-run Feng,Zheng-song Zhao. [J]. Front. Eng, 2014, 1(1): 42-51.

关键词: construction management     technology innovation     UHPC trestle panel    

cannulation of superior vena cava for a hemodialysis patient with an original dysfunctional catheter on the left

null

《医学前沿(英文)》 2017年 第11卷 第3期   页码 445-448 doi: 10.1007/s11684-017-0520-0

摘要:

Establishing a long-term vascular access in patients exhibiting vascular access exhaustion is challenging. In this study, we reported a case of a direct catheterization in the superior vena cava of a hemodialysis patient with vascular access exhaustion and original dysfunctional catheter inserted via the left internal jugular vein. The direct catheterization was performed with cuffed tunnel catheter (CUFF) and guided by digital subtraction angiography (DSA) and multidetector computed tomography venography (MDCTV). The DSA and MDCTV results revealed an occlusion in the right innominate vein and thromboses in the left innominate, right internal jugular, subclavian, and femoral veins. The distal end of the superior vena cava was localized clearly by the original CUFF under DSA. Directed at the distal end of the superior vena cava, a 0.5-cm secondary puncture was introduced below the lateral head of the sternocleidomastoid muscle via the right neck area. This study is one of the few reports regarding direct catheterization of CUFF via the superior vena cava of a patient with vascular access exhaustion and CUFF dysfunction on the left internal jugular vein. We believe that our study can provide a new alternative for inserting central venous catheter for such patient.

关键词: superior vena cava     intervention     vascular access exhaustion     catheterization     tunneled cuffed hemodialysis catheter    

Chaotic behavior of LNG after stratification in main stream region of storage tank

WANG Jingjing, MA Xiaoqian

《能源前沿(英文)》 2008年 第2卷 第4期   页码 514-518 doi: 10.1007/s11708-008-0076-4

摘要: A study of the chaotic behavior of liquefied natural gas (LNG) after stratification in the main stream region of a storage tank was conducted. Based on non-linear dynamics, a 2-dimensional Rayleigh-Benard convection model was developed to simulate the convection, Lorenz equations of LNG convection were deduced from conservation equations, and the Runge-Kutta method was used to solve the equations. The results showed that when = 1.33, 106 < < 1470, chaos was obtained, which meant that the velocity field and the temperature field were highly unsteady. In addition, the influence of temperature and scale factor on the solutions and the corresponding range of parameters were studied. The results revealed that the chaos in LNG convection resulted from the interaction of buoyancy and viscid forces. A small quantity of heat impacting the storage tank would lead to a strong and unstable convection of LNG in the main stream region.

关键词: Runge-Kutta     non-linear     corresponding     temperature     addition    

Analytical solution for SH wave propagating through a graded plate of metamaterial

Jinfeng ZHAO, Yongdong PAN, Zheng ZHONG

《机械工程前沿(英文)》 2011年 第6卷 第3期   页码 301-307 doi: 10.1007/s11465-011-0238-7

摘要:

A physical model for the shear horizontal (SH) wave propagating from left-handed material (LHM) through a graded or transition layer to right-handed material (RHM) has been proposed in this paper. After the comparison of the basic wave equations of the electromagnetic, longitudinal, and SH waves, it is found that they take similar differential form. The analytical solutions have been found for power law, hyperbolic, and polynomial profiles. Numerical waveforms of the amplitude and phase of the displacement are obtained for the corresponding profiles. It is found that the waveforms are symmetric for the power law and hyperbolic profiles, and that the waveform for the polynomial profile is shifted and non-symmetric. The shift along with the anti-symmetric profile may provide a way to monitor the wave behavior of the metamaterials.

关键词: left-handed material (LHM)     metamaterial     shear horizontal (SH) wave    

The main achievements in the past 24 years and the prospects of mechanism research in China

ZOU Hui-jun, ZHANG Long, ZHANG Qing

《机械工程前沿(英文)》 2006年 第1卷 第3期   页码 249-259 doi: 10.1007/s11465-006-0038-7

摘要: Since 1982, the symposiums on mechanism in China has been held fifteen times. In the past 24 years, Chinese mechanism has experienced a phenomenal development. Generally, fundamental research on traditional mechanisms is enhanced; mechanism and creative design of products are closely combined; modern mechanism with advanced and new technology is opened up; and mechanism is promoted to modernization. These are manifested in the following aspects: theory research on analysis and synthesis of traditional mechanism is deeply developed; computer-aided design on mechanisms is realized vigorously; conceptual design of mechanism system and mechanical products is energetically pushed; research on robot mechanisms and its industrial application is deeply developed; research on analysis and synthesis of controllable mechanisms and compliant mechanisms are energetically carried out; research on the dynamics of mechanisms and machines is vigorously developed; and reformation of teaching contents and system of mechanism is energetically carried out. Through the above-mentioned aspects of theory research and practical application, the theoretical and academic levels of Chinese mechanism can be considered at the advanced international level. However, there are not many original and breakthrough research achievements of fundamental research in China. In the meantime, there is a larger gap in the aspect of practical application of mechanism in the country compared with advanced countries in the world.

关键词: above-mentioned     developed     Generally     reformation     breakthrough research    

Construction technology on pile foundation of No. 6 main pier in Dashengguan Yangtze Bridge

Hongbin YU , Zeping LIAN ,

《结构与土木工程前沿(英文)》 2009年 第3卷 第3期   页码 339-343 doi: 10.1007/s11709-009-0047-9

摘要: Based on pile foundation construction of No. 6 main pier, deep mudstone geological foundation and deep-water construction in Nanjing-Dashengguan Yangtze Bridge, the method of super-large-diameter bored pile in deep water is studied. The spread drill, application of PHP mud, and choice of machine are solved by adopting two machines of KTY4000 and KPG300A. Besides, the airlift reversing circulation is selected in slag discharge. The results show that this method can ensure successfully the construction of pier foundation to satisfy the demands of codes.

关键词: PHP slurry     KTY4000 drilling machine     KPG3000A drilling machine     spread drill    

Construction management and technical innovation of the main project of Hong Kong–Zhuhai–Macao Bridge

Yongling ZHU, Jinwen ZHANG, Xinglin GAO

《工程管理前沿(英文)》 2018年 第5卷 第1期   页码 128-132 doi: 10.15302/J-FEM-2018201

摘要: Design Units: CCCC Highway Consultants Co., Ltd.; China Zhongtie Major Bridge Reconnaissance & Design Institute Co., Ltd. Construction Units: China Communications Construction Company Limited Consortium; China Railway Shanhaiguan Bridge Group Co., Ltd.; Wuhan Heavy Engineering Co., Ltd.; CCCC First Harbor Engineering Company Ltd. Consortium; Guangdong Changda Highway Engineering Co., Ltd.; China ZhongTie Major Bridge Engineering Group Co., Ltd. Consortium; Chongqing Zhixiang Paving Technology Engineering Co., Ltd.; Hunan Construction Engineering Group; China Railway Electrification Bureau Group Co., Ltd. Consortium Supervision Units: China Railway Wuhan Bridge Engineering Consulting Supervision Co., Ltd. Consortium; China Classification Society Industrial Corp.; Wuhan Bridge and Building Works Supervision Co., Ltd.; Tiesiyuan (Hubei) Engineering Supervision Consulting Co., Ltd. Consortium; Xi’an Fangzhou Engineering Consulting Co., Ltd. Consortium; Guangdong Zhonggong Project Management Co., Ltd.; Chongqing Zhongyu Engineering Consultation and Supervision Co., Ltd. Consortium

关键词: Major Bridge     Zhongtie Major     Engineering Group     Bureau Group     Construction Company    

标题 作者 时间 类型 操作

Drug-coated balloon-only strategy for percutaneous coronary intervention of left main coronary artery

期刊论文

Contemporary coronary artery bypass grafting

null

期刊论文

Incremental value of contrast echocardiography in the diagnosis of left ventricular noncompaction

null

期刊论文

Challenges and opportunities in improving left ventricular remodelling and clinical outcome following

期刊论文

Key technological innovations in the construction of the main terminal of Beijing Daxing International

期刊论文

Evaluation of potential failure of rock slope at the left abutment of Jinsha River Bridge by model test

Zhiming ZHAO, Xihua WANG

期刊论文

The main and added effects of heat on mortality in 33 Chinese cities from 2007 to 2013

期刊论文

Optimization of the main liming process for inulin crude extract from Jerusalem artichoke tubers

Huandong LI, Hongji ZHU, Jianjun QIAO, Junhu DU, Hua ZHANG

期刊论文

Construction management and technology innovation for main projects of Quanzhou Bay Bridge

Jun DU, Fangwen WENG

期刊论文

cannulation of superior vena cava for a hemodialysis patient with an original dysfunctional catheter on the left

null

期刊论文

Chaotic behavior of LNG after stratification in main stream region of storage tank

WANG Jingjing, MA Xiaoqian

期刊论文

Analytical solution for SH wave propagating through a graded plate of metamaterial

Jinfeng ZHAO, Yongdong PAN, Zheng ZHONG

期刊论文

The main achievements in the past 24 years and the prospects of mechanism research in China

ZOU Hui-jun, ZHANG Long, ZHANG Qing

期刊论文

Construction technology on pile foundation of No. 6 main pier in Dashengguan Yangtze Bridge

Hongbin YU , Zeping LIAN ,

期刊论文

Construction management and technical innovation of the main project of Hong Kong–Zhuhai–Macao Bridge

Yongling ZHU, Jinwen ZHANG, Xinglin GAO

期刊论文